Protein Core

       It is the mission of the Protein Core facility (PCF) to support and advance research capabilities at the Center by providing high quality protein and antigen purification support. The PFC is located at Tulane HSC and its major goal is to provide LVC/SLIIDR researchers with purified protein antigen for use in vaccine research.

       PCF personnel dedicated to LVC/SLIIDR projects will assist researchers in the selection of optimal recombinant expression systems (prokaryotic and eukaryotic), will sub-clone genes of interest into expression vectors, and will optimize protein expression and purification. The core will also assist in generating site-directed mutants of proteins of interest and in scaling up of recombinant protein production.

       Emphasis is placed on purity, with removal of bacterial endotoxin and contaminating immunogens from protein preparations, while minimizing degradation.

Location:

Tulane School of Medicine